Lansoprazol Farmoz may be available in the countries listed below.
Lansoprazole is reported as an ingredient of Lansoprazol Farmoz in the following countries:
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Etoposido Rontag may be available in the countries listed below.
Etoposide is reported as an ingredient of Etoposido Rontag in the following countries:
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Levotiroxina Sodica Perugen may be available in the countries listed below.
Levothyroxine sodium salt (a derivative of Levothyroxine) is reported as an ingredient of Levotiroxina Sodica Perugen in the following countries:
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Kyowacron may be available in the countries listed below.
Gliclazide is reported as an ingredient of Kyowacron in the following countries:
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Generic Name: Acetazolamide Sodium
Class: Carbonic Anhydrase Inhibitors
ATC Class: S01EC01
VA Class: CV703
CAS Number: 59-66-5
Carbonic anhydrase inhibitor; nonbacteriostatic sulfonamide derivative.a b c d e
Adjunctive treatment of open-angle or secondary glaucoma.c d e
Short-term use in acute angle-closure glaucoma to lower intraocular pressure (IOP) before surgery.a b c d e Should not be used for long-term treatment of angle-closure glaucoma.b c d e (See Contraindications under Cautions.)
Prevention or amelioration of symptoms (e.g., headache, lassitude, insomnia, nausea, shortness of breath, dizziness) associated with acute mountain sickness.a b c d f
Shortens the time of acclimatization.f If acute mountain sickness develops, shortens duration; does not obviate need to stop ascent or to descend.f
Also used in the treatment and prevention of high-altitude sleep disorders.c d f Decreases periodic breathing and apnea and improves oxygenation.f
Management (in combination with other anticonvulsants) of centrencephalic epilepsies (e.g., petit mal, unlocalized seizures);c e may be ineffective for prolonged therapy.a b Has not been evaluated in controlled clinical studies in specific seizure types.a b
Adjunctive treatment of edema due to CHF or drug therapy.b c e Less potent diuretic than thiazide diuretics; metabolic acidosis resulting in loss of diuretic effect occurs after 2–4 days of continuous therapy.b
Has been used in the treatment of hyperkalemic and hypokalemic forms of periodic paralysis†.b
Administer orally or by direct IV injection.c d e
Do not administer IM; injection is painful.b e
When an oral liquid preparation is needed, crush the appropriate number of tablets and suspend in a highly flavored carbohydrate syrup.a Can suspend up to 500 mg of acetazolamide in 5 mL of syrup; suspensions containing 250 mg per 5 mL are more palatable.a Alternatively, soften a tablet in 2 teaspoonsful of hot water and add 2 teaspoonsful of honey or syrup; swallow immediately.a
When the extended-release capsules are used for glaucoma, if adequate response is not achieved with twice-daily administration of this preparation, consider using other acetazolamide preparations that are administered more frequently (i.e., tablet, parenteral preparation) to achieve IOP control.d
For solution and drug compatibility information, see Compatibility under Stability.
Administer IV when rapid lowering of IOP is necessary or if patient is unable to take oral medication.a e
Reconstitute vial containing 500 mg of acetazolamide with 5 mL of sterile water for injection to provide a solution containing 100 mg/mL.a e
Available as acetazolamide (oral preparations) and acetazolamide sodium; dosage expressed in terms of acetazolamide.c d e
Adjust dosage based on patient response and requirements.a
8–30 mg/kg or 300–900 mg/m2 daily in 3 divided doses has been used.a
Children ≥12 years of age: 500 mg twice daily as extended-release capsules.d
Children ≥12 years of age: 500 mg twice daily as extended-release capsules.d
5–10 mg/kg every 6 hours has been used.a
Children ≥12 years of age: 500 mg once or twice daily as extended-release capsules.d Initiate 24–48 hours before ascent; continue for 48 hours while at high altitude or longer if needed to control symptoms.d
8–30 mg/kg daily in divided doses has been used.a c
5 mg/kg or 150 mg/m2 once daily in the morning has been used.a
Conventional tablets: 250 mg to 1 g daily.c For daily dosages >250 mg, administer in divided doses.c
Extended-release capsules: 500 mg twice daily.d
250 mg to 1 g daily.e For daily dosages >250 mg, administer in divided doses.e
Conventional tablets: 250 mg every 4 hours.c Some patients respond to short-term therapy with 250 mg twice daily.c
Extended-release capsules: 500 mg twice daily.d
250 mg every 4 hours.e Some patients respond to short-term therapy with 250 mg twice daily.e
Conventional tablets: 250 mg every 4 hours. a c Alternatively, 250 mg twice daily or an initial dose of 500 mg followed by 125–250 mg every 4 hours.a c
Extended-release capsules: 500 mg twice daily.d
250 mg every 4 hours.e Alternatively, 250 mg twice daily or an initial dose of 500 mg followed by 125–250 mg every 4 hours.e
Conventional tablets and extended-release capsules: 500 mg to 1 g daily in divided doses.c d Initiate 24–48 hours before ascent; continue for 48 hours while at high altitude or longer if needed to control symptoms.c d
125–250 mg twice daily starting 24 hours before ascent has been effective for prevention of acute mountain sickness; 500 mg (as extended-release capsules) every 24 hours also has been effective.f 750 mg daily may be more effective than 500 mg daily.f
125 mg at bedtime has been used for the management of high-altitude sleep disorders.f
For treatment of acute mountain sickness, some experts recommend 250 mg given within 24 hours of onset of symptoms and a second 250-mg dose 8 hours later.f
Conventional tablets: 8–30 mg/kg daily in divided doses.c
Usual dosage range: 375 mg to 1 g daily.c
When used in conjunction with other anticonvulsants, initiate at 250 mg once daily and increase dosage as needed.c
8–30 mg/kg daily in divided doses; usual dosage range is 375 mg to 1 g daily.e
When given in conjunction with other anticonvulsants, initiate at 250 mg once daily and increase dosage as needed.e
Conventional tablets: Initially, 250–375 mg (5 mg/kg) once daily in the morning.c
If patient fails to lose edema fluid after initial response, hold drug for 1 day. c To avoid loss of diuretic effect, administer intermittently (on alternate days or for 2 days followed by a drug-free day).c
Initially, 250–375 mg (5 mg/kg) once daily in the morning.e
If patient fails to lose edema fluid after initial response, hold drug for 1 day.e To avoid loss of diuretic effect, administer intermittently (on alternate days or for 2 days followed by a drug-free day).e
Conventional tablets: 250–375 mg once daily for 1 or 2 days, alternating with a drug-free day.c
250–375 mg once daily for 1 or 2 days, alternating with a drug-free day.e
250 mg 2 to 3 times daily has been used.a
When used in glaucoma or seizure disorders, dosage >1 g daily is not associated with additional clinical benefit.c d e
When used for diuresis, increasing dosage does not produce greater response and may result in decreased response.c d e
Select dosage with caution because of age-related decreases in hepatic, renal, and/or cardiac function and concomitant disease and drug therapy.d
Marked impairment of hepatic function.c d e Cirrhosis.c d e (See Hepatic Impairment under Cautions.)
Depressed serum concentrations of sodium and/or potassium.c d e
Adrenocortical insufficiency.c d e
Hyperchloremic acidosis.c d e
Marked impairment of renal function.c d e
Long-term treatment of angle-closure glaucoma; further closure of the angle may occur while worsening of glaucoma is masked by lower IOP.b c d e
Hypersensitivity to acetazolamide or any ingredients in the formulation.c d e
Serious adverse events (e.g., Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, agranulocytosis, aplastic anemia, other blood dyscrasias) associated with sulfonamide therapy possible.b c d e
Discontinue if signs of hypersensitivity, blood dyscrasias, or other serious reactions occur.b c e
Drowsiness and/or paresthesia reported with high dosages.b c d e
Caution in patients with pulmonary obstruction, emphysema, or advanced pulmonary disease where alveolar ventilation may be impaired.b c d e Acetazolamide may precipitate or aggravate acidosis in these patients.c d e
Monitor for hematologic reactions associated with sulfonamides; obtain a CBC and platelet count before therapy and periodically during therapy.c d e Discontinue the drug if clinically important changes occur.c d e
Monitor serum electrolytes periodically for electrolyte imbalances (i.e., hyponatremia, hypokalemia, metabolic acidosis).c d e
Increased or decreased blood glucose concentrations reported.d Caution in patients with impaired glucose tolerance or diabetes mellitus.b
Category C.c d e
Discontinue nursing or the drug.c d e
Conventional tablets and parenteral preparation: Manufacturers state that safety and efficacy not established.c e
Extended-release capsules: Safety and efficacy not established in pediatric patients <12 years of age. d
Growth retardation has been reported in children receiving long-term therapy with extended-release capsules.d
Risk of metabolic acidosis (may be severe) in geriatric patients with reduced renal function.d
Avoid use in patients with marked hepatic impairment, including those with cirrhosis, because of the risk of developing hepatic encephalopathy.c d e (See Contraindications.)
Avoid use in patients with marked renal impairment.c d e (See Contraindications.)
Paresthesias, hearing dysfunction or tinnitus, anorexia, altered taste, nausea, vomiting, diarrhea, polyuria, drowsiness, confusion.c e
Drug or Test | Interaction | Comments |
|---|---|---|
Amphetamine | Decreased urinary excretion of amphetamines; potentiates the effects of amphetaminesd | |
Amphotericin B | Possible enhanced potassium depletionb | |
Antidiabetic agents (oral agents, insulin) | May interfere with the hypoglycemic responseb | |
Aspirin | Increased risk of toxicityc d e | Avoid concomitant use in patients receiving high-dose aspirinc d e h |
Carbonic anhydrase inhibitors, topical | Additive systemic effectsd g | Concomitant use not recommendedd g |
Corticosteroids | Possible enhanced potassium depletionb | |
Cyclosporine | Possible increased plasma cyclosporine concentrationsd | |
Digitalis glycosides | Acetazolamide-induced hypokalemia may potentiate toxicity of digitalisb | |
Folic acid antagonists | Potential antifolate effectd | |
Lithium | Increased renal excretion of lithium and decreased lithium concentrationsd | Monitor patientb |
Methenamine | May interfere with urinary antiseptic effect of methenamined | |
Phenytoin | Altered metabolism of phenytoin; increased serum phenytoin concentrations; increased risk of phenytoin-associated osteomalaciab d | Caution advisedd |
Primidone | Possible decreased serum concentration of primidone and its metabolites; possible decreased anticonvulsant effectd | Caution advisedd |
Quinidine | Decreased urinary excretion of quinidined | |
Sodium bicarbonate | Increased risk of renal calculusd | |
Tests for urinary protein | False-positive results with tests that use bromophenol blue reagent (Albustix) or sulfosalicylic acidb | |
Tests, theophylline concentrations | Interferes with high-performance liquid chromatography (HPLC) assay for theophyllined |
Well absorbed from GI tract.a b Peak plasma concentrations attained within 1–4 or 3–6 hours following administration of conventional tablets or extended-release capsules, respectively.d
Following IV administration, reduction in IOP occurs in 2 minutes.b
Following administration of conventional tablets or extended-release capsules, reduction in IOP occurs in 1 or 2 hours, respectively.b
Following IV administration, reduction in IOP persists for 4–5 hours.b
Following administration of conventional tablets or extended-release capsules, reduction in IOP persists for 8–12 or 18–24 hours, respectively.b d
Extended-release capsules: Food does not affect absorption.d
Distributed into erythrocytes, renal cortex, and aqueous humor of eye.a d
Crosses the placenta.a b
Distributed into milk in dogs; not known whether distributed into human milk.a
Excreted principally in the urine as unchanged drug.a
Tight, light-resistant container at 15–30°C.c
20–25°C.d
15–30°C.e
Reconstituted solutions prepared using sterile water for injection are stable for 3 days at 2–8°C or 12 hours at 15–30°C.e
Use reconstituted solutions within 12 hours to minimize the risk of microbial contamination.e
For information on systemic interactions resulting from concomitant use, see Interactions.
Compatible |
|---|
Dextran 6% in dextrose 5% |
Dextran 6% in sodium chloride 0.9% |
Dextrose–Ringer's injection combinations |
Dextrose-Ringer’s injection, lactated, combinations |
Dextrose-saline combinations |
Dextrose 2½, 5, or 10% in water |
Fructose 10% in sodium chloride 0.9% |
Fructose 10% in water |
Invert sugar 5 and 10% in sodium chloride 0.9% |
Invert sugar 5 and 10% in water |
Ionosol products |
Ringer's injection |
Ringer's injection, lactated |
Sodium chloride 0.45 or 0.9% |
Sodium lactate (1/6) M |
Compatible |
|---|
Cimetidine HCl |
Ranitidine HCl |
Variable |
|---|
Diltiazem HCl |
Noncompetitive reversible inhibitor of the carbonic anhydrase enzyme.b d c e
Reduces the formation of hydrogen and bicarbonate ions from carbon dioxide and water, thereby reducing availability of these ions for active transport into secretions.b
Decreases aqueous humor secretion and IOP.b c d
Increases urinary excretion of bicarbonate, sodium, and potassium due to decrease in hydrogen ions in the renal tubules.b Decreases reabsorption of water, increases urine volume, urine becomes alkaline.b
When used as a diuretic, plasma bicarbonate concentration is decreased and chloride concentration may be increased, resulting in metabolic acidosis.b In the presence of acidosis, diuretic effect ceases.b
In acute mountain sickness, the effect of acetazolamide on acid-base balance (i.e., increased renal excretion of bicarbonate that leads to metabolic acidosis) results in compensatory hyperventilation and improved oxygenation.f
Exact mechanism of anticonvulsant activity unclear; may be due to metabolic acidosis, inhibition of carbonic anhydrase in the CNS, or other mechanisms.b
Risk of adverse effects, including sensitivity reactions; discontinue therapy and consult clinician if signs of sensitivity occur.c d e
When used to prevent acute mountain sickness, importance of gradual ascent.c f Use of acetazolamide does not obviate need to stop ascent if acute mountain sickness develops or descend if severe forms of altitude sickness (e.g., high attitude pulmonary or cerebral edema) occur.c f
Potential for the drug to impair mental alertness or impair vision (myopia); use caution when driving a vehicle or operating machinery until effects on individual are known.d
Advise patients with pulmonary obstruction or emphysema that the drug may precipitate or aggravate acidosis.c d
Advise patients with diabetes or impaired glucose tolerance that increases and decreases in blood glucose have occurred in acetazolamide-treated patients.d
Importance of informing clinicians of existing or contemplated concomitant therapy, including prescription and OTC drugs (e.g., high-dose aspirin), as well as concomitant diseases.c d e
Importance of women informing clinicians if they are or plan to become pregnant or plan to breast-feed.c d e
Importance of informing patients of other precautionary information.c d e (See Cautions.)
Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details.
* available from one or more manufacturer, distributor, and/or repackager by generic (nonproprietary) name
Routes | Dosage Forms | Strengths | Brand Names | Manufacturer |
|---|---|---|---|---|
Oral | Capsules, extended-release | 500 mg | Diamox | Duramed |
Tablets | 125 mg* | Acetazolamide Tablets | Mutual, Taro, United Research | |
250 mg* | Acetazolamide Tablets | Lannett, Mutual, Taro, Watson |
* available from one or more manufacturer, distributor, and/or repackager by generic (nonproprietary) name
Routes | Dosage Forms | Strengths | Brand Names | Manufacturer |
|---|---|---|---|---|
Parenteral | For injection, for IV use | 500 mg (of acetazolamide)* | Acetazolamide Sodium for Injection | Bedford, Hospira |
This pricing information is subject to change at the sole discretion of DS Pharmacy. This pricing information was updated 03/2011. Actual costs to patients will vary depending on the use of specific retail or mail-order locations and health insurance copays.
AcetaZOLAMIDE 125MG Tablets (TARO): 90/$45.99 or 180/$79.98
AcetaZOLAMIDE 250MG Tablets (LANNETT): 60/$37.99 or 180/$89.97
AcetaZOLAMIDE 500MG 12-hr Capsules (ZYDUS PHARMACEUTICALS (USA)): 100/$310.01 or 300/$909.95
Diamox Sequels 500MG 12-hr Capsules (TEVA PHARMACEUTICALS USA): 60/$329.59 or 180/$955.83
This report on medications is for your information only, and is not considered individual patient advice. Because of the changing nature of drug information, please consult your physician or pharmacist about specific clinical use.
The American Society of Health-System Pharmacists, Inc. and Drugs.com represent that the information provided hereunder was formulated with a reasonable standard of care, and in conformity with professional standards in the field. The American Society of Health-System Pharmacists, Inc. and Drugs.com make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information and specifically disclaims all such warranties. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the information is provided for informational purposes only. The entire monograph for a drug should be reviewed for a thorough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc. and Drugs.com do not endorse or recommend the use of any drug. The information is not a substitute for medical care.
AHFS Drug Information. © Copyright, 1959-2011, Selected Revisions September 2007. American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland 20814.
† Use is not currently included in the labeling approved by the US Food and Drug Administration.
a. AHFS drug information 2007. McEvoy GK, ed. Acetazolamide. Bethesda, MD: American Society of Health-System Pharmacists; 2007: 2880-1.
b. AHFS drug information 2007. McEvoy GK, ed. Carbonic Anhydrase Inhibitors General Statement. Bethesda, MD: American Society of Health-System Pharmacists; 2007: 2877-80.
c. Mutual Pharmaceutical Company, Inc. Acetazolamide tablet prescribing information. Philadelphia, PA; 2001 Sept.
d. Duramed Pharmaceuticals, Inc. Diamox (acetazolamide) extended release capsule prescribing information. Pomona, NY; 2005 Apr.
e. Bedford Laboratories. Acetazolamide injection powder, lyophilized, for solution prescribing information. Bedford, OH; 2002 Oct.
f. Committee to Advice on Tropical Medicine and Travel (CATMAT). Statement on high-altitude illnesses: an advisory committee statement (ACS). Can Commun Dis Rep. 2007; 33:1-20.
g. Alcon. Azopt (brinzolamide) ophthalmic suspension 1% prescribing information. Fort Worth, TX; 2003 Dec.
h. AHFS Drug Information 2007. McEvoy GK, ed. Salicylates General Statement. Bethesda, MD: American Society of Health-System Pharmacists. 2007:2011-23.
HID. Trissel LA. Handbook on injectable drugs. 14th ed. Bethesda, MD: American Society of Health-System Pharmacists; 2007:3-5.
Acebutolol Sandoz may be available in the countries listed below.
Acebutolol hydrochloride (a derivative of Acebutolol) is reported as an ingredient of Acebutolol Sandoz in the following countries:
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Amcopan may be available in the countries listed below.
Scopolamine butylbromide (a derivative of Scopolamine) is reported as an ingredient of Amcopan in the following countries:
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Cyclix may be available in the countries listed below.
In some countries, this medicine may only be approved for veterinary use.
Cloprostenol is reported as an ingredient of Cyclix in the following countries:
Cloprostenol sodium salt (a derivative of Cloprostenol) is reported as an ingredient of Cyclix in the following countries:
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Piperacilline / Tazobactam Orchid may be available in the countries listed below.
Piperacillin sodium salt (a derivative of Piperacillin) is reported as an ingredient of Piperacilline / Tazobactam Orchid in the following countries:
Tazobactam sodium salt (a derivative of Tazobactam) is reported as an ingredient of Piperacilline / Tazobactam Orchid in the following countries:
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The following drugs and medications are in some way related to, or used in the treatment of Iron Poisoning, Acute. This service should be used as a supplement to, and NOT a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
Carboplatino Delta Farma may be available in the countries listed below.
Carboplatin is reported as an ingredient of Carboplatino Delta Farma in the following countries:
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Moscontin may be available in the countries listed below.
Morphine is reported as an ingredient of Moscontin in the following countries:
Morphine sulphate pentahydrate (a derivative of Morphine) is reported as an ingredient of Moscontin in the following countries:
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Cilroton may be available in the countries listed below.
Domperidone is reported as an ingredient of Cilroton in the following countries:
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Contalax may be available in the countries listed below.
Bisacodyl is reported as an ingredient of Contalax in the following countries:
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BAR-ee-um SUL-fate
In the U.S.
In Canada
Available Dosage Forms:
Therapeutic Class: Diagnostic Agent, Radiological Contrast Media
Barium sulfate is a radiopaque agent. Radiopaque agents are used to help diagnose certain medical problems. Since radiopaque agents are opaque to (block) x-rays, the areas of the body in which they are localized will appear white on the x-ray film. This creates the needed distinction, or contrast, between one organ and other tissues. The contrast will help the doctor see any special conditions that may exist in that organ or part of the body.
Barium sulfate is taken by mouth or given rectally by enema. If taken by mouth, it makes the esophagus, the stomach, and/or the small intestine opaque to the x-rays so that they can be "photographed". If it is given by enema, the colon and/or the small intestine can be seen and photographed by x-rays.
The dose of barium sulfate will be different for different patients and depends on the type of test. The strength of the suspension and tablet is determined by how much barium they contain. Different tests will require a different strength and amount of suspension (some may require the tablet form), depending on the age of the patient, the contrast needed, and the x-ray equipment used.
Barium sulfate is to be used only by or under the direct supervision of a doctor.
In deciding to use a diagnostic test, any risks of the test must be weighed against the good it will do. This is a decision you and your doctor will make. Also, other things may affect test results. For this test, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to barium sulfate or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Although there is no specific information comparing use of barium sulfate in children with use in other age groups, this agent is not expected to cause different side effects or problems in children than it does in adults.
This contrast agent has been used in older people and has not been shown to cause different side effects or problems in them than it does in younger adults.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
The presence of other medical problems may affect the use of this diagnostic test. Make sure you tell your doctor if you have any other medical problems, especially:
The dose of barium sulfate will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of barium sulfate. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
Make sure to drink plenty of liquids after the test. Otherwise, barium sulfate may cause severe constipation.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
See also: barium sulfate Oral, Rectal side effects (in more detail)
The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.
The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.
Generic Name: pyrithione (Topical route)
pir-i-THYE-one
In the U.S.
Available Dosage Forms:
Therapeutic Class: Dermatological Agent
Chemical Class: Pyrethrums
Pyrithione is used to help control the symptoms of dandruff and seborrheic dermatitis of the scalp.
This medicine is available without a prescription.
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Although there is no specific information comparing use of pyrithione in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children than it does in adults.
Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of pyrithione in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
This section provides information on the proper use of a number of products that contain pyrithione. It may not be specific to DHS Zinc. Please read with care.
For best results, use this medicine at least 2 times a week or as directed by your doctor.
To use:
Keep this medicine away from the eyes. If you should accidentally get some in your eyes, flush them thoroughly with water.
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
If your condition does not get better after regular use of this medicine, or if it gets worse, check with your doctor.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
See also: DHS Zinc Topical side effects (in more detail)
The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.
The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.
Abacavir Elea may be available in the countries listed below.
Abacavir is reported as an ingredient of Abacavir Elea in the following countries:
International Drug Name Search
In the US, Enablex (darifenacin systemic) is a member of the drug class urinary antispasmodics and is used to treat Overactive Bladder and Urinary Incontinence.
US matches:
Darifenacin is reported as an ingredient of Enablex in the following countries:
Darifenacin hydrobromide (a derivative of Darifenacin) is reported as an ingredient of Enablex in the following countries:
International Drug Name Search
Sicadol may be available in the countries listed below.
Mefenamic Acid is reported as an ingredient of Sicadol in the following countries:
International Drug Name Search
Otrivina may be available in the countries listed below.
Xylometazoline hydrochloride (a derivative of Xylometazoline) is reported as an ingredient of Otrivina in the following countries:
International Drug Name Search
Generic Name: zinc oxide topical (ZINK OX ide)
Brand Names: ARC, Balmex, Boudreaux Butt Paste, Caldesene, Calmol-4 Suppository, Critic-Aid Skin Paste, Delazinc, Dermagran BC, Desitin, Desitin Maximum Strength Original, Desitin Rapid Relief Creamy, Diaper Rash Ointment, Diaper Relief, Dr. Smith's Diaper, Flanders Buttocks Ointment, Geri-Protect, Medi-Paste, PeriGuard, Pinxav, Rash Relief, RVPaque, Seniortopix Healix, Soothe & Cool Skin Paste, Sportz Block Dark, Sportz Block Light, Sportz Block Medium, Triple Paste, Tronolane Suppositories, Unna-Flex Elastic Unna Boot 3 inch, Unna-Flex Elastic Unna Boot 4 inch, Znlin
Zinc oxide is a mineral.
Zinc oxide topical (for the skin) is used to treat diaper rash, minor burns, severely chapped skin, or other minor skin irritations.
Zinc oxide rectal suppositories are used to treat itching, burning, irritation, and other rectal discomfort caused by hemorrhoids or painful bowel movements.
Zinc oxide topical may also be used for purposes not listed in this medication guide.
Zinc oxide topical will not treat a bacterial or fungal infection. Call your doctor if you have any signs of infection such as redness and warmth or oozing skin lesions.
Keep the diaper area clean and dry to prevent worsening of skin rash. Change wet diapers as soon as possible. Allow the skin to dry thoroughly before putting on a fresh diaper.
Avoid using other medications on the areas you treat with zinc oxide unless you doctor tells you to.
Zinc oxide topical will not treat a bacterial or fungal infection. Call your doctor if you have any signs of infection such as redness and warmth or oozing skin lesions.
Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Apply enough of this medication to cover the entire area to be treated. Zinc oxide often leaves a thin white residue that may not be entirely rubbed in.
To treat chapped skin, minor burn wounds, or other skin irritations, use the medication as often as needed. Apply a thin layer to the affected area and rub in gently.
To treat diaper rash, use this medication each time the diaper is changed. It is especially important to apply the medication at bedtime or whenever there will be a long period of time between diaper changes.
Keep the diaper area clean and dry to prevent worsening of skin rash. Change wet diapers as soon as possible. Allow the skin to dry thoroughly before putting on a fresh diaper.
Zinc oxide rectal suppositories come with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
Try to empty your bowel and bladder just before using the suppository. Cleanse and dry your rectal area thoroughly.
Remove the outer wrapper from the suppository before inserting it. Avoid handling the suppository too long or it will melt in your hands.
For best results, stay lying down after inserting the suppository and hold it in your rectum for a few minutes. The suppository will melt quickly once inserted and you should feel little or no discomfort while holding it in.
Since zinc oxide is used on an as needed basis, you are not likely to miss a dose. Using extra zinc oxide to make up a missed dose will not make the medication more effective.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Avoid applying other skin medications on the same treatment area with zinc oxide, unless your doctor has told you to.
There may be other drugs that can interact with zinc oxide topical or rectal suppositories. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
See also: Rash Relief side effects (in more detail)
Namicin may be available in the countries listed below.
Lomefloxacin hydrochloride (a derivative of Lomefloxacin) is reported as an ingredient of Namicin in the following countries:
International Drug Name Search
Generic Name: dextrose 5% in water (injection) (DEX trose)
Brand Names:
Dextrose is a form of glucose (sugar). Dextrose 5% in water is injected into a vein through an IV to replace lost fluids and provide carbohydrates to the body.
Dextrose 5% in water is used to treat low blood sugar (hypoglycemia), insulin shock, or dehydration (fluid loss). Dextrose 5% in water is also given for nutritional support to patients who are unable to eat because of illness, injury, or other medical condition.
Dextrose 5% in water is sometimes used as a diluent (liquid) for preparing injectable medication in an IV bag. A diluent provides a large amount of fluid in which to dilute a small amount of medicine. The diluent helps carry the medicine into your bloodstream through the IV. This helps your caregivers inject the medicine slowly and more safely into your body.
Dextrose 5% in water may also be used for purposes not listed in this medication guide.
Before using dextrose 5% in water, tell your doctor if you have diabetes, breathing problems, an electrolyte imbalance, kidney or liver disease, a food or drug allergy, or if you receive regular blood transfusions.
Do not mix dextrose 5% in water with any medication that has not been prescribed by your doctor. If you are using the injections at home, be sure you understand how to properly mix and store your medicine.
To make sure you can safely use dextrose 5% in water, tell your doctor if you have any of these other conditions:
diabetes;
breathing problems;
an electrolyte imbalance (such as low levels of potassium in your blood);
kidney or liver disease;
any allergy to foods or medicines; or
if you receive regular blood transfusions.
Dextrose 5% in water is injected into a vein through an IV. You may be shown how to use an IV at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.
Before using dextrose 5% in water, check the solution container to make sure there are no leaks in it. Use only the needle type and size recommended by your doctor or caregivers.
You may need to mix dextrose 5% in water with another medication in an IV bag before using it. Do not mix dextrose 5% in water with any medication that has not been prescribed by your doctor. If you are using the injections at home, be sure you understand how to properly mix and store your medicine.
Call your doctor or tell your caregivers if your catheter, needle, or IV tubing becomes blocked or if the solution is not flowing normally.
If you receive this medication in a hospital or clinic setting your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely. Your blood sugar may also need to be tested often during treatment. If you use the medicine at home, visit your doctor regularly. Do not miss any follow up visits to your doctor for blood or urine tests.
Use a disposable needle only once. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.
Call your doctor for instructions if you miss a dose of dextrose 5% in water.
Overdose symptoms may include severe forms of some of the side effects listed in this medication guide.
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
severe burning, pain, or swelling around the IV needle;
warmth, redness, oozing, or bleeding where the IV was placed;
fever, ongoing cough;
high blood sugar (increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss);
headache, trouble concentrating, memory problems, weakness, feeling unsteady, hallucinations, fainting, seizure, shallow breathing or breathing that stops;
low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling); or
anxiety, sweating, pale skin, severe shortness of breath, wheezing, pain, fast or uneven heart rate.
Less serious side effects may include:
mild irritation around the IV needle;
upset stomach; or
swelling in your hands or feet.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
It is not likely that other drugs you take orally or inject will have an effect on Dextrose 5% in Water. But many drugs can interact with each other. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Generic Name: acetaminophen, chlorpheniramine, and phenylephrine (a SEET a MIN oh fen, KLOR fen EER a meen, FEN ill EFF rin)
Brand Names: Alka-Seltzer Plus Cold, Allergy Relief Multi-Symptom, Comtrex Flu Therapy, Comtrex Severe Cold & Sinus, Contac Cold+Flu, Dristan Cold Multi Symptom Formula, Protid, Robitussin Nighttime Nasal Relief, Sinus Congestion & Pain Nighttime, Tylenol Allergy Multi-Symptom, Tylenol Children's Plus Cold, Tylenol Sinus Congestion and Pain Cool Burst Day Night, Tylenol Sinus Congestion Nighttime
Acetaminophen is a pain reliever and fever reducer.
Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).
The combination of acetaminophen, chlorpheniramine, and phenylephrine is used to treat headache, fever, body aches, runny or stuffy nose, sneezing, itching, watery eyes, and sinus congestion caused by allergies, the common cold, or the flu.
Acetaminophen, chlorpheniramine, and phenylephrine may also be used for purposes not listed in this medication guide.
Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:
liver disease, cirrhosis, or a history of alcoholism;
a blockage in your digestive tract (stomach or intestines);
diabetes;
kidney disease;
epilepsy or other seizure disorder;
cough with mucus, or cough caused by smoking, emphysema, or chronic bronchitis;
enlarged prostate or urination problems;
low blood pressure;
pheochromocytoma (an adrenal gland tumor); or
if you take potassium (Cytra, Epiklor, K-Lyte, K-Phos, Kaon, Klor-Con, Polycitra, Urocit-K).
Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. This medicine is usually taken only for a short time until your symptoms clear up.
Measure liquid medicine with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
Drop the effervescent tablets into a glass of water (at least 4 ounces, or one-half cup). Stir this mixture and drink all of it right away.
Do not take for longer than 7 days in a row. Stop taking the medicine and call your doctor if you still have a fever after 3 days of use, you still have pain after 7 days (or 5 days if treating a child), if your symptoms get worse, or if you have a skin rash, ongoing headache, or any redness or swelling.
Since this medicine is taken when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.
Overdose symptoms may also include severe forms of some of the side effects listed in this medication guide.
chest pain, rapid pulse, fast or uneven heart rate;
confusion, hallucinations, severe nervousness;
tremor, seizure (convulsions);
easy bruising or bleeding, unusual weakness;
urinating less than usual or not at all;
nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of your skin or eyes); or
dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, chest pain, shortness of breath, uneven heartbeats, seizure).
Less serious side effects may include:
dizziness, drowsiness;
mild headache;
dry mouth, nose, or throat;
constipation;
blurred vision;
feeling nervous; or
sleep problems (insomnia);
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Tell your doctor about all other medicines you use, especially:
leflunomide (Arava);
topiramate (Topamax);
zonisamide (Zonegran);
an antibiotic, antifungal medicine, sulfa drug, or tuberculosis medicine;
an antidepressant;
birth control pills or hormone replacement therapy;
bladder or urinary medications;
blood pressure medication;
a bronchodilator;
cancer medicine;
cholesterol-lowering medications such as Lipitor, Niaspan, Zocor, Vytorin, and others;
gout or arthritis medications (including gold injections);
HIV/AIDS medication;
medication for nausea and vomiting, stomach ulcers, or irritable bowel syndrome;
medicines to treat psychiatric disorders;
an NSAID such as Advil, Aleve, Arthrotec, Cataflam, Celebrex, Indocin, Motrin, Naprosyn, Treximet, Voltaren, others; or
seizure medication.
This list is not complete and other drugs may interact with acetaminophen, chlorpheniramine, and phenylephrine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
See also: Dryphen side effects (in more detail)
