Deconamine

Pronunciation: klor-fen-IHR-ah-meen/sue-do-eh-FED-rin
Generic Name: Chlorpheniramine/Pseudoephedrine
Brand Name: Examples include Deconamine and Sudafed Plus

Deconamine is used for:

Relieving symptoms of sinus congestion, sinus pressure, runny nose, and sneezing due to colds, upper respiratory infections, and allergies. It may also used to treat other conditions as determined by your doctor.

Deconamine is an antihistamine and decongestant combination. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing. The decongestant promotes sinus and nasal drainage, relieving congestion and pressure.

Do NOT use Deconamine if:

• you are allergic to any ingredient in Deconamine


• you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems


• you take sodium oxybate (GHB) or if you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Deconamine:

Some medical conditions may interact with Deconamine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a fast, slow, or irregular heartbeat


• if you have a history of asthma, lung problems (eg, emphysema), adrenal gland problems (eg, adrenal gland tumor), heart problems, high blood pressure, diabetes, heart blood vessel problems, stroke, glaucoma, a blockage of your stomach or intestines, ulcers, a blockage of your bladder, trouble urinating, an enlarged prostate, seizures, or an overactive thyroid

Some MEDICINES MAY INTERACT with Deconamine. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin,MAOIs (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Deconamine's side effects


• Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased


• Bromocriptine or hydantoins (eg, phenytoin) because the risk of their side effects may be increased by Deconamine


• Guanethidine, guanadrel, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Deconamine

This may not be a complete list of all interactions that may occur. Ask your health care provider if Deconamine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Deconamine:

Use Deconamine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Deconamine by mouth with or without food.


• If you miss a dose of Deconamine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Deconamine.

Important safety information:

• Deconamine may cause dizziness, drowsiness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Deconamine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Do not take diet or appetite control medicines while you are taking Deconamine without checking with you doctor.


• Deconamine has pseudoephedrine and chlorpheniramine in it. Before you start any new medicine, check the label to see if it has pseudoephedrine or chlorpheniramine in it too. If it does or if you are not sure, check with your doctor or pharmacist.


• Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.


• If your symptoms do not get better within 5 to 7 days or if they get worse, check with your doctor.


• Deconamine may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Deconamine. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.


• Deconamine may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Deconamine for a few days before the tests.


• Tell your doctor or dentist that you take Deconamine before you receive any medical or dental care, emergency care, or surgery.


• Use Deconamine with caution in the ELDERLY; they may be more sensitive to its effects.


• Caution is advised when using Deconamine in CHILDREN; they may be more sensitive to its effects.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Deconamine while you are pregnant. It is not known if Deconamine is found in breast milk. Do not breast-feed while taking Deconamine.

Possible side effects of Deconamine:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; trouble sleeping; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Deconamine side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; severe dizziness, lightheadedness, or headache; severe drowsiness; seizures; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Deconamine:

Store Deconamine at room temperature, between 59 and 86 degrees F (15 and 30 degrees C) away from heat, moisture, and light. Do not store in the bathroom. Keep Deconamine out of the reach of children and away from pets.

General information:

• If you have any questions about Deconamine, please talk with your doctor, pharmacist, or other health care provider.


• Deconamine is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Deconamine. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Deconamine resources

• Deconamine Side Effects (in more detail)
• Deconamine Use in Pregnancy & Breastfeeding
• Deconamine Drug Interactions
• Deconamine Support Group
• 2 Reviews for Deconamine - Add your own review/rating

• Deconamine Concise Consumer Information (Cerner Multum)


• AccuHist Drops Prescribing Information (FDA)


• Histade Concise Consumer Information (Cerner Multum)

Compare Deconamine with other medications

• Hay Fever
• Sinusitis

C Tuck

C Tuck may be available in the countries listed below.

Ingredient matches for C Tuck

Ascorbic Acid

Ascorbic Acid is reported as an ingredient of C Tuck in the following countries:

• Japan

International Drug Name Search

Gravinate

Gravinate may be available in the countries listed below.

Ingredient matches for Gravinate

Dimenhydrinate

Dimenhydrinate is reported as an ingredient of Gravinate in the following countries:

• Ethiopia


• Myanmar

International Drug Name Search

Dyrenium

Pronunciation: trye-AM-ter-een
Generic Name: Triamterene
Brand Name: Dyrenium

Dyrenium may cause high blood potassium levels that can be fatal if not corrected. High blood potassium levels occur more commonly in patients with kidney problems, diabetes, elderly patients, those who are severely ill, or patients who are not taking an agent used to increase excretion of potassium. If you develop muscle weakness or irregular heartbeat, notify your doctor immediately.

Dyrenium is used for:

Treating swelling (edema) associated with conditions such as congestive heart failure, cirrhosis of the liver, and certain severe kidney problems (eg, nephrosis). It may be used alone or with other medicines. It may also be used for other conditions as determined by your doctor.

Dyrenium is a potassium-sparing diuretic. It works by making the kidneys eliminate sodium (salt) and water from the body while retaining potassium.

Do NOT use Dyrenium if:

• you are allergic to any ingredient in Dyrenium


• you are taking potassium supplements, another potassium-sparing diuretic (eg, amiloride), or an aldosterone blocker (eg, eplerenone)


• you are unable to urinate or have high blood potassium levels or severely decreased liver or kidney function

Contact your doctor or health care provider right away if any of these apply to you.

Before using Dyrenium:

Some medical conditions may interact with Dyrenium. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have heart problems, diabetes, kidney damage caused by diabetes, liver or kidney problems, low blood sodium levels, a high acidity of body fluids, dehydration, or a history of kidney stones

Some MEDICINES MAY INTERACT with Dyrenium. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Aldosterone blockers (eg, eplerenone), angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), angiotensin II receptor antagonists (eg, valsartan), cyclosporine, penicillin G potassium, otherpotassium-sparing diuretics (eg, amiloride), or potassium supplements because high blood potassium levels may occur and cause listlessness, confusion, abnormal skin sensations of the arms and legs, heaviness of the limbs, slow or irregular heartbeat, or stopping of the heart


• Insulin and oral hypoglycemics (eg, chlorpropamide) because the risk of side effects, such as severe low blood sodium and changes in blood sugar, may be increased


• Lithium because risk of side effects and toxicity may be increased by Dyrenium


• Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, indomethacin) because the effectiveness of Dyrenium may be decreased and the risk of kidney problems and high blood potassium levels may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Dyrenium may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Dyrenium:

Use Dyrenium as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Dyrenium by mouth with or without food.


• Dyrenium may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm.


• If you miss a dose of Dyrenium, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Dyrenium.

Important safety information:

• Dyrenium may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Dyrenium with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Check with your doctor before you use a salt substitute or a product that has potassium in it.


• Tell your doctor or dentist that you take Dyrenium before you receive any medical or dental care, emergency care, or surgery.


• LAB TESTS, including blood electrolytes, blood cell counts, kidney and liver function tests, blood uric acid levels, and blood pressure, may be performed while you use Dyrenium. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Use Dyrenium with caution in the ELDERLY; they may be more sensitive to its effects.


• Dyrenium should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: It is not known if Dyrenium can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Dyrenium while you are pregnant. It is not known if Dyrenium is found in breast milk. Do not breast-feed while taking Dyrenium.

Possible side effects of Dyrenium:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; headache; loss of appetite; nausea; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); dry mouth; excessive thirst; slow or irregular heart rate; unusual muscle weakness; unusual tiredness; vomiting; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Dyrenium side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include lightheadedness; nausea; vomiting; weakness.

Proper storage of Dyrenium:

Store Dyrenium at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Dyrenium out of the reach of children and away from pets.

General information:

• If you have any questions about Dyrenium, please talk with your doctor, pharmacist, or other health care provider.


• Dyrenium is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Dyrenium. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Dyrenium resources

• Dyrenium Side Effects (in more detail)
• Dyrenium Use in Pregnancy & Breastfeeding
• Drug Images
• Dyrenium Drug Interactions
• Dyrenium Support Group
• 0 Reviews for Dyrenium - Add your own review/rating

• Dyrenium Prescribing Information (FDA)


• Dyrenium Advanced Consumer (Micromedex) - Includes Dosage Information


• Dyrenium Concise Consumer Information (Cerner Multum)


• Dyrenium Monograph (AHFS DI)


• Triamterene Professional Patient Advice (Wolters Kluwer)

Compare Dyrenium with other medications

• Ascites
• Edema

Veyxyl

Veyxyl may be available in the countries listed below.

In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Veyxyl

Amoxicillin

Amoxicillin trihydrate (a derivative of Amoxicillin) is reported as an ingredient of Veyxyl in the following countries:

• Germany

International Drug Name Search

Forifek

Forifek may be available in the countries listed below.

Ingredient matches for Forifek

Cefaclor

Cefaclor monohydrate (a derivative of Cefaclor) is reported as an ingredient of Forifek in the following countries:

• Indonesia

International Drug Name Search

Lorafast

Lorafast may be available in the countries listed below.

Ingredient matches for Lorafast

Dexamethasone

Dexamethasone is reported as an ingredient of Lorafast in the following countries:

• Peru

Loratadine

Loratadine is reported as an ingredient of Lorafast in the following countries:

• Peru


• Vietnam

International Drug Name Search

Optipar

Optipar may be available in the countries listed below.

Ingredient matches for Optipar

Paroxetine

Paroxetine hydrochloride (a derivative of Paroxetine) is reported as an ingredient of Optipar in the following countries:

• Finland

International Drug Name Search

Cefium

Cefium may be available in the countries listed below.

Ingredient matches for Cefium

Cefprozil

Cefprozil monohydrate (a derivative of Cefprozil) is reported as an ingredient of Cefium in the following countries:

• Greece

International Drug Name Search

Optivar

In the US, Optivar (azelastine ophthalmic) is a member of the drug class ophthalmic antihistamines and decongestants and is used to treat Conjunctivitis, Allergic.

US matches:

• Optivar Drops


• Optivar

Ingredient matches for Optivar

Azelastine

Azelastine hydrochloride (a derivative of Azelastine) is reported as an ingredient of Optivar in the following countries:

• United States

International Drug Name Search

Dicloxacilina La Santé

Dicloxacilina La Santé may be available in the countries listed below.

Ingredient matches for Dicloxacilina La Santé

Dicloxacillin

Dicloxacillin is reported as an ingredient of Dicloxacilina La Santé in the following countries:

• Colombia

International Drug Name Search

Ascotyl

Ascotyl may be available in the countries listed below.

In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Ascotyl

Tylosin

Tylosin tartrate (a derivative of Tylosin) is reported as an ingredient of Ascotyl in the following countries:

• Italy

International Drug Name Search

Bo Ana

In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Bo Ana

Famphur

Famphur is reported as an ingredient of Bo Ana in the following countries:

• United States

International Drug Name Search

Omicool

Omicool may be available in the countries listed below.

Ingredient matches for Omicool

Omeprazole

Omeprazole is reported as an ingredient of Omicool in the following countries:

• India

International Drug Name Search

Denagard

Dosage Form: FOR ANIMAL USE ONLY
Denagard-Liquid Concentrate

Denagard®

(tiamulin)

Liquid Concentrate

12.3% Tiamulin hydrogen fumarate

NADA 140-916, Approved by FDA

One Quart

(32fl oz; 946mL)

Warning:

Keep out of reach of children. Avoid direct contact with the skin. Direct contact with skin or mucous membranes may cause irritation.

Withdraw medicated water 3 days before slaughter after use at 3.5 mg per pound and 7 days before slaughter after use at 10.5 mg per pound.

Active Ingredient:

This bottle contains 4.10 oz (116.4 g) tiamulin hydrogen fumarate in solution.

Caution:

For use in animals only – Not for human use.

Prepare fresh medicated water daily. Use as the only source of drinking water for 5 days. The effects of tiamulin on swine reproductive performance, pregnancy and lactation have not been determined.

Contraindication:

Swine being treated with Denagard (tiamulin) should not have access to feeds containing polyether ionophores (e.g., monensin, lasalocid, narasin, salinomycin and semduramicin) as adverse reactions may occur.

Indications:

Treatment of swine dysentery associated with Brachyspira (formerly Serpulina or Treponema) hyodysenteriae and swine pneumonia due to Actinobacillus pleuropneumoniae, susceptible to tiamulin.

Use Directions:

Do not use undiluted.

This bottle contains 116,400 mg tiamulin hydrogen fumarate for use in preparing medicated drinking water for swine. See package insert for complete directions, read completely.

Protect from direct sunlight. Store at controlled room temperature, 59°-86°F (15°-30°C).

Restricted Drug (California): Use only as directed

Denagard® is a registered trademark of Novartis AG

U.S. Patent No. 4,278,674

Product # 701

NAH/DEN-LC/BL/2

Marketed by:

Novartis Animal Health US, Inc.

Greensboro, NC 27408 U.S.A.

NADA 140-916, Approved by FDA

Denagard®

(tiamulin)

Liquid Concentrate

Description:

Denagard (tiamulin) Liquid Concentrate is a solution containing 12.3% tiamulin hydrogen fumarate (w/v) in an aqueous solution. The active ingredient, tiamulin, chemically is 14-desoxy-14-[(2-diethylaminoethyl) mercaptoacetoxy] mutilin hydrogen fumarate, a semi-synthetic diterpene antibiotic. Denagard Liquid Concentrate is for use only in preparing medicated drinking water for swine.

Actions:

Tiamulin is active against Brachyspira (formerly Serpulina or Treponema) hyodysenteriae and Actinobacillus pleuropneumoniae. It is readily absorbed from the gut and can be found in the blood within 30 minutes after dosing.

Indications:

Denagard (tiamulin), when administered in the drinking water for five consecutive days, is an effective antibiotic for the treatment of swine dysentery associated with Brachyspira (formerly Serpulina or Treponema) hyodysenteriae susceptible to tiamulin at a dose level of 3.5 mg tiamulin hydrogen fumarate per pound of body weight daily and for treatment of swine pneumonia due to Actinobacillus pleuropneumoniae susceptible to tiamulin when given at 10.5 mg tiamulin hydrogen fumarate per pound of body weight daily.

Contraindications:

Swine being treated with Denagard (tiamulin) should not have access to feeds containing polyether ionophores (e.g., monensin, lasalocid, narasin, salinomycin and semduramicin) as adverse reactions may occur.

Warning:

Keep out of reach of children. Avoid contact with skin. Direct contact with skin or mucous membranes may cause irritation.

Withdraw medicated water 3 days before slaughter after treatment at 3.5 mg per pound and 7 days before slaughter following treatment at 10.5 mg per pound body weight.

Caution:

For use in drinking water of swine only. Prepare fresh medicated water daily. The effects of tiamulin on swine reproductive performance, pregnancy and lactation have not been determined. For animal use only – not for use in humans.

Adverse Reactions:

Overdoses of Denagard have sometimes produced transitory salivation, vomiting and an apparent calming effect on the pig. If signs of toxicity occur, discontinue use of medicated water and replace with clean, fresh water.

In rare cases, redness of the skin primarily over the ham and underline has been observed during medication. If these signs appear, discontinue use of this drug. Provide ample clean drinking water. Thoroughly rinse (hose down) the housing to remove urine and feces from animal contact surfaces or move the animals to clean pens. If the condition persists, consult your veterinarian.

Studies to evaluate the safety of the water soluble form of tiamulin in breeding swine have not been done.

Use Directions:

The concentration of tiamulin in the drinking water must be adjusted to compensate for variation in water consumption due to weight or size of the pig, environmental temperature and other factors. It is important that pigs receive the proper drug dose, 3.5 mg tiamulin hydrogen fumarate per pound for swine dysentery or 10.5 mg tiamulin hydrogen fumarate per pound for swine pneumonia, each day for 5 consecutive days.

Table 1 Approximate daily water consumption per pig.

Pig Weight, lb	Water Intake, gal.	Pig Weight, lb	Water Intake, gal.
20	0.3 - 0.5	125	1.0 – 2.0
45	0.4 – 1.1	180	1.2 – 3.0
75	0.7 – 1.5

Note:

1. Prepare fresh medicated drinking water every day for the 5 day treatment period.
   


2. Water medicated with Denagard should be the only source of drinking water during the treatment period.

Directions for preparing Denagard medicated solutions: Determine the amount of Denagard Liquid Concentrate needed to medicate the desired volume of drinking water at the proper concentration. Carefully measure out this amount, add it to the water and stir to thoroughly mix.

Table 2 Denagard Liquid Concentrate

			One Quart
Net tiamulin hydrogen fumarate content:			116,400 mg
Diseases to be treated:			Swine Dysentery	Swine Pneumonia
Daily tiamulin hydrogen fumarate required per pound body weight:			3.5 mg	10.5 mg
Required treatment duration:			5 days	5 days
Pig body weight this bottle will treat for ONE day:			33,257 lb	11,086 lb
Number of pigs this bottle will treat for ONE day:		Pig Wt, lb
		20	1,663	554
		45	739	246
		75	443	148
		125	266	88
		180	185	62
Suggested final dilution of:		1 bottle	512 gal	-
		3 bottles	-	512 gal
		½ pint (8 oz)	128 gal	43 gal
		1½ pints (24 oz)	-	128 gal
Tiamulin hydrogen fumarate concentration per gallon at suggested final dilution*			227 mg (60 ppm)	681 mg (180 ppm)

*Note: Increase or decrease dilution rate as required to obtain proper daily drug dose.

Directions for using Denagard in medicated proportioners: One quart of Denagard Liquid Concentrate mixed with water to make four gallons of stock solution and this stock solution metered at one fluid ounce per gallon will provide 227 mg of tiamulin hydrogen fumarate per gallon to 512 gallons of drinking water for treatment of swine dysentery. Three quarts of Denagard Liquid Concentrate mixed with water to make four gallons of stock solution and this stock solution metered at one fluid ounce per gallon will provide 681 mg tiamulin hydrogen fumarate per gallon to a total of 512 gallons of drinking water for treatment of swine pneumonia.

One pint of Denagard Liquid Concentrate mixed with water to make two gallons of stock solution and this stock solution metered at one fluid ounce per gallon will provide 227 mg of tiamulin hydrogen fumarate per gallon to 256 gallons of drinking water for treatment of swine dysentery. Use three pints of Denagard Liquid Concentrate in two gallons of stock solution to be metered at one fluid ounce per gallon to deliver 681 mg per gallon to a total of 256 gallons of drinking water for treatment of swine pneumonia.

One-half pint (8 fluid ounces) of Denagard Liquid Concentrate diluted with water to make one gallon of stock solution and this stock solution metered at one fluid ounce of drinking water with a medication proportioner will provide 227 mg of tiamulin hydrogen fumarate per gallon to 128 gallons of drinking water for treatment of swine dysentery.

Use one and one-half pints of Denagard Liquid Concentrate per gallon of stock solution to be metered at one fluid ounce per gallon to provide 681 mg per gallon to 128 gallons of drinking water for treatment of swine pneumonia.

In barrels or tanks: Three fluid ounces of Denagard Liquid Concentrate will medicate 48 gallons of drinking water at 227 mg per gallon for treatment of swine dysentery or 16 gallons at 681 mg per gallon for treatment of swine pneumonia.

Measure Denagard Liquid concentrate carefully, pour into the proper amount of water and thoroughly mix. The concentration of tiamulin hydrogen fumarate in the stock solution and in the drinking water delivered must be adjusted to compensate for variation in water consumption by pigs due to body weight, environmental and other factors. It is important that the pigs receive the proper drug dose of 3.5 mg of tiamulin hydrogen fumarate per pound of body weight daily for 5 consecutive days for treatment of swine dysentery or a dose of 10.5 mg per pound body weight daily for 5 consecutive days for treatment of swine pneumonia.

Attention: If no response to treatment is obtained within 5 days re-establish the diagnosis. Failure of response may be related to the presence of non-susceptible organisms of other complicating disease conditions. Because of the tendency for the disease to recur on premises with a history of swine dysentery or with swine pneumonia, a control program should be implemented after treatment. Drugs are not substitutes for proper sanitary measures or good management, but should be used in conjunction with such practices.

How supplied:

Container Size	Active Ingredients
Quart bottles	12.3% (116.4g)
(32 fl oz; 946 mL)	Tiamulin hydrogen fumarate

Protect from direct sunlight. Store at controlled room temperature, 59°-86°F (15°-30°C).

Observe expiration date.

U.S. Patent No. 4,278,674

Principal Display Panel

Denagard® 

(tiamulin)

Liquid Concentrate

12.3% Tiamulin

hydrogen fumarate

NADA 140-916,

Approved by FDA

One Quart

(32 fl oz; 946 mL)

NOVARTIS

ANIMAL HEALTH

Denagard  tiamulin  solution, concentrate

Product Information Product Type OTC ANIMAL DRUG NDC Product Code (Source) 58198-0701 Route of Administration ORAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength TIAMULIN FUMARATE (TIAMULIN) TIAMULIN FUMARATE 0.123 g  in 1 mL

Inactive Ingredients Ingredient Name Strength No Inactive Ingredients Found

Product Characteristics Color      Score      Shape Size Flavor Imprint Code Contains

Packaging # NDC Package Description Multilevel Packaging 1 58198-0701-1 946 mL In 1 BOTTLE None

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
NADA	NADA140916	01/29/1993

Labeler - Novartis Animal Health US, Inc. (966985624)

Revised: 12/2010Novartis Animal Health US, Inc.

DuetDHA Balanced

Dosage Form: tablets / capsules
Duet®DHA Balanced by StuartNatal®

Rx Only

DESCRIPTION:

Duet® DHA Balanced is a gluten free prescription regimen of prenatal multi-vitamin, multi-mineral, and omega-3 fatty acids, supplied as tablets and enteric-coated softgel capsules.

Each yellow oval Duet® Tablet* contains:

VITAMINS
A (beta carotene)	2,850 IU
C (ascorbic acid)	120 mg
D (cholecalciferol)	840 IU
E (dl-alpha tocopheryl acetate)	3 mg
B1 (thiamine mononitrate)	1.8 mg
B2 (riboflavin)	4 mg
Niacinamide	20 mg
B6 (pyridoxine hydrochloride)	50 mg
Folic acid	1 mg
B12 (cyanocobalamin)	12 mcg
MINERALS
Calcium (calcium carbonate)	219 mg
Iron (polysaccharide iron complex and        sodium iron EDTA, Ferrazone®)	27 mg
Magnesium (magnesium oxide)	25 mg
Zinc (zinc oxide)	25 mg
Copper (cupric oxide)	2 mg
Iodine	220 mcg

Each frosted golden-colored oval enteric-coated DHA Softgel Capsule* contains a clear solution of not less than 430 mg purified omega-3 long-chain fatty acids including DHA (docosahexaenoic acid), EPA (eicosapentaenoic acid) and DPA (docasapentaenoic acid) in no more than 754 mg of fish oil.

OMEGA-3 FATTY ACIDS
Total omega-3 long-chain fatty acids	No less than 430 mg
As DHA	No less than 295 mg
As other omega-3 long-chain fatty acids	No less than 135 mg

OTHER INGREDIENTS (Duet® Tablet): Acacia, corn starch, croscarmellose sodium, D&C Yellow No. 10, dicalcium phosphate, dl-alpha tocopherol, FD&C Yellow No. 6, food starch, gelatin, glucose, hydroxypropyl methycellulose, hypromellose, lecithin, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, silicon dioxide, sodium ascorbate, sodium benzoate, sorbic acid, sucrose, talc, triglycerides, titanium dioxide, xanthan gum.

OTHER INGREDIENTS (Enteric-coated DHA Softgel Capsule): Ammonium hydroxide, ethylcellulose, fractionated coconut oil, gelatin, glycerin, oleic acid, stearic acid, sodium alginate, and DHA and EPA concentrate derived from purified fish oil via a proprietary process.

*Compliance: The yellow oval Duet® Tablet is formulated in conformance with official U.S. Pharmacopeia (USP) standards of quality for potency, purity and dissolution. Duet® Tablet, as manufactured, is subject to Quality Control Standards and Good Manufacturing Practices established by the U.S. FDA. The DHA concentrate complies with The Global Organization for EPA and DHA Omega-3s (GOED) Voluntary Monograph for identity and purity. The DHA concentrate is also certified to meet Friend of the Sea Sustainable Fisheries criteria.

INDICATIONS:

Duet® DHA Balanced is a gluten free prescription regimen of prenatal multi-vitamin, multi-mineral, and omega-3 fatty acid supplements indicated for use in improving the nutritional status of women throughout pregnancy and in the post-natal period for both lactating and non-lactating mothers. Duet® DHA Balanced is also useful in improving the nutritional status prior to conception.

CONTRAINDICATIONS:

This product is contraindicated in patients with known hypersensitivity to any of the ingredients, including fish or fish oil.

WARNINGS:

Folic acid alone is improper therapy in the treatment of pernicious anemia and other megaloblastic anemias where Vitamin B12 is deficient.

WARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or a poison control center immediately.

Since daily ingestion of more than 3 grams per day of omega-3 fatty acids (including alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA)) from fish oils may have potential antithrombotic activities and may increase bleeding times, administration of DHA should be avoided in patients with inherited or acquired bleeding diatheses, including those taking anticoagulants.

PRECAUTIONS:

Folic acid in doses above 0.1 mg daily may obscure the diagnosis of pernicious anemia (hematologic remission may occur while neurological manifestations remain progressive).

DRUG INTERACTIONS:

Pyridoxine supplements should be avoided in patients receiving levodopa alone, as the actions of levodopa may be antagonized.

ADVERSE REACTIONS:

Allergic sensitization has been reported following both oral and parenteral administration of folic acid.

DOSAGE AND ADMINISTRATION:

Before, during and after pregnancy, one tablet and one enteric-coated softgel capsule taken by mouth daily, or as directed by a physician. The tablet and enteric-coated softgel capsule may be taken together or at different times of the day. Caution should be exercised to ensure that the prescribed dose of DHA does not exceed 1 gram (1,000 mg) per day.

HOW SUPPLIED:

NDC 66479-895-30. Duet® DHA Balanced is supplied in child-resistant blister cards containing 30 doses per carton (1 Duet® tablet and 1 enteric-coated DHA softgel capsule equals 1 daily dose). Each unit-of-use dispensing carton contains 5 cards with 6 unit-doses per card which is a 30-day supply. The yellow oval Duet® tablet is imprinted with the StuartNatal® logo (“heart-in-a-heart”) on one side and “123” on the other. The frosted golden-colored oval enteric-coated DHA softgel capsule is imprinted with the StuartNatal® logo (“heart-in-a-heart” outlined traced) on one side and X1 on the other.

STORAGE: Store at controlled room temperature 20-25°C (68-77°F). Protect from moisture and excessive heat. Note that contact with moisture may produce surface discoloration of the tablet.

DISPENSING: Keep in a well-closed, light-resistant container as defined by the USP. Unit dose blisters are child-resistant to opening as a safeguard against ingestion by children. KEEP THIS AND ALL MEDICATIONS OUT OF REACH OF CHILDREN.

To request medical information or to report suspected adverse reactions, contact Xanodyne Medical Affairs at 1-877-773-7793.

www.DuetDHA.com

Marketed by: Xanodyne® pharmaceuticals, inc.

         Newport, KY 41071, USA

StuartNatal, Duet, “When one heart becomes two” and the “heart-in-a-heart” logo are registered trademarks of Xanodyne Pharmaceuticals, Inc. All rights reserved.

Ferrazone® is a registered trademark of AkzoNobel b v

© 2011, Xanodyne® Pharmaceuticals, Inc.

PI-895-B     Revision 01/2011

Principal Display Panel

Blister Pack Label

Duet®DHA

Balanced

Rx Only

Lot No. 99-999999

Exp. Date 99/9999

SEE WARNING ON CARTON

Xanodyne® Pharmaceuticals, inc.

Newport, KY 41071

NDC 66479-895-91

Carton Label

Rx Only

NDC 66479-895-30

when one heart

becomes two®

Duet®DHA

Balanced

Prescription Prenatal Vitamins

Features an innovative blend of iron

and enteric-coated omega-3

long-chain fatty acids(DHA

and EPA) for enhanced

tolerability8

30 day supply-30 tablets

And 30 softgel capsules

By StuartNatal®

GLUTEN FREE

And 430 mg

Omega-3s

DuetDHA Balanced  beta carotene, ascorbic acid, cholecalciferol, .alpha.-tocopherol acetate, dl-, thiamine mononitrate, riboflavin, niacinamide, pyridoxine hydrochloride, folic acid, cyanocobalamin, calcium carbonate, iron, magnesium oxide, zinc oxide, cupric oxide, iodine, omega-3 fatty acids  kit

Product Information Product Type HUMAN PRESCRIPTION DRUG NDC Product Code (Source) 66479-895

Packaging # NDC Package Description Multilevel Packaging 1 66479-895-30 1 KIT In 1 BLISTER PACK None

QUANTITY OF PARTS Part # Package Quantity Total Product Quantity Part 1   6  Part 2   6

Part 1 of 2 DuetDHA Balanced  beta carotene, ascorbic acid, cholecalciferol, .alpha.-tocopherol acetate, dl-, thiamine mononitrate, riboflavin, niacinamide, pyridoxine hydrochloride, folic acid, cyanocobalamin, calcium carbonate, iron, magnesium oxide, zinc oxide, cupric oxide, iodine  tablet

Product Information       Route of Administration ORAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength BETA CAROTENE (BETA CAROTENE) BETA CAROTENE 2850 [iU] ASCORBIC ACID (ASCORBIC ACID) ASCORBIC ACID 120 mg CHOLECALCIFEROL (CHOLECALCIFEROL) CHOLECALCIFEROL 840 [iU] .ALPHA.-TOCOPHEROL ACETATE, DL- (.ALPHA.-TOCOPHEROL ACETATE, DL-) .ALPHA.-TOCOPHEROL ACETATE, DL- 3 mg THIAMINE MONONITRATE (THIAMINE) THIAMINE MONONITRATE 1.8 mg RIBOFLAVIN (RIBOFLAVIN) RIBOFLAVIN 4 mg NIACINAMIDE (NIACINAMIDE) NIACINAMIDE 20 mg PYRIDOXINE HYDROCHLORIDE (PYRIDOXINE) PYRIDOXINE HYDROCHLORIDE 50 mg FOLIC ACID (FOLIC ACID) FOLIC ACID 1 mg CYANOCOBALAMIN (CYANOCOBALAMIN) CYANOCOBALAMIN 12 ug CALCIUM CARBONATE (CALCIUM) CALCIUM CARBONATE 219 mg IRON (IRON) IRON 27 mg MAGNESIUM OXIDE (MAGNESIUM) MAGNESIUM OXIDE 25 mg ZINC OXIDE (ZINC) ZINC OXIDE 25 mg CUPRIC OXIDE (CUPRIC CATION) CUPRIC OXIDE 2 mg IODINE (IODINE) IODINE 220 ug

Inactive Ingredients Ingredient Name Strength ACACIA   STARCH, CORN   CROSCARMELLOSE SODIUM   D&C YELLOW NO. 10   ANHYDROUS DIBASIC CALCIUM PHOSPHATE   .ALPHA.-TOCOPHEROL, DL-   FD&C YELLOW NO. 6   GELATIN   DEXTROSE   HYPROMELLOSES   LECITHIN, SOYBEAN   MAGNESIUM STEARATE   CELLULOSE, MICROCRYSTALLINE   POLYETHYLENE GLYCOL   POLYVINYL ALCOHOL   SILICON DIOXIDE   SODIUM ASCORBATE   SODIUM BENZOATE   SORBIC ACID   SUCROSE   TALC   MEDIUM-CHAIN TRIGLYCERIDES   TITANIUM DIOXIDE   XANTHAN GUM

Product Characteristics Color yellow (yellow) Score no score Shape OVAL (OVAL) Size 19mm Flavor Imprint Code 123 Contains

Packaging # NDC Package Description Multilevel Packaging Package Information Not Applicable

Marketing Information Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date unapproved drug other 11/19/2010 02/28/2013

Part 2 of 2 DuetDHA Balanced  omega-3 fatty acids  capsule, liquid filled

Product Information       Route of Administration ORAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength OMEGA-3 FATTY ACIDS (OMEGA-3 FATTY ACIDS) OMEGA-3 FATTY ACIDS 430 mg

Inactive Ingredients Ingredient Name Strength AMMONIA   ETHYLCELLULOSES   MEDIUM-CHAIN TRIGLYCERIDES   GELATIN   GLYCERIN   OLEIC ACID   STEARIC ACID   SODIUM ALGINATE

Product Characteristics Color yellow (yellow) Score no score Shape OVAL (OVAL) Size 16mm Flavor Imprint Code X1 Contains

Packaging # NDC Package Description Multilevel Packaging Package Information Not Applicable

Marketing Information Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date unapproved drug other 11/19/2010 02/28/2013

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
unapproved drug other		11/19/2010	02/28/2013

Labeler - Xanodyne Pharmaceuticals, Inc. (012921305)

Establishment
Name	Address	ID/FEI	Operations
JLM Pharmatech, Inc.		966721805	MANUFACTURE

Establishment
Name	Address	ID/FEI	Operations
Accucaps Industries Limited		248441727	MANUFACTURE

Establishment
Name	Address	ID/FEI	Operations
Perrigo Holland, Inc.		085893071	MANUFACTURE

Revised: 05/2011Xanodyne Pharmaceuticals, Inc.

Floraquin

Floraquin may be available in the countries listed below.

Ingredient matches for Floraquin

Diiodohydroxyquinoline

Diiodohydroxyquinoline is reported as an ingredient of Floraquin in the following countries:

• Turkey

International Drug Name Search

R-Tanna Tablets

phenylephrine tannate and chlorpheniramine tannate

Dosage Form: tablet
R-Tanna Tablets

Description

R-Tanna Tablets are an antihistamine/nasal decongestant combination. Each tablet contains:

Phenylephrine Tannate         25 mg

Chlorpheniramine Tannate      9 mg


Other ingredients: corn starch, dibasic calcium phosphate, magnesium stearate, methylcellulose, polygalacturonic acid, povidone, talc.

Clinical Pharmacology

R-Tanna Tablets combine the sympathomimetic decongestant effect of phenylephrine with the antihistaminic action of chlorpheniramine.

Indications and Usage

R-Tanna Tablets are indicated for symptomatic relief of the coryza and nasal congestion associated with the common cold, sinusitis, allergic rhinitis and other upper respiratory tract conditions. Appropriate therapy should be provided for the primary disease.

Contraindications

R-Tanna Tablets are contraindicated for newborns, nursing mothers and patients sensitive to any of the ingredients or related compounds.

Warnings

Use with caution in patients with hypertension, cardiovascular disease, hyperthyroidism, diabetes, narrow angle glaucoma or prostatic hypertrophy. Use with caution or avoid use in patients taking monoamine oxidase (MAO) inhibitors, or within 14 days of stopping such treatment. This product contains an antihistamine which may cause drowsiness and may have additive central nervous system (CNS) effects with alcohol or other CNS depressants (e.g., hypnotics, sedatives, tranquilizers).

Precautions

General: Antihistamines are more likely to cause dizziness, sedation and hypotension in elderly patients. Antihistamines may cause excitation, particularly in children, but their combination with sympathomimetics may cause either mild stimulation or mild sedation.

Information for patients: Caution patients against drinking alcoholic beverages or engaging in potentially hazardous activities requiring alertness, such as driving a car or operating machinery while using this product. Patients should be warned not to use this product if they are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If patients are uncertain whether a prescription drug contains an MAOI, they should be instructed to consult a health professional before taking such a product.

Drug interactions: MAO inhibitors may prolong and intensify the anticholinergic effects of antihistamines and the overall effects of sympathomimetic agents.

Carcinogenesis, mutagenesis, impairment of fertility: No long term animal studies have been performed with R-Tanna Tablets.

Pregnancy: Teratogenic effects: Pregnancy Category C. Animal reproduction studies have not been conducted with R-Tanna Tablets. It is also not known whether R-Tanna Tablets can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. R-Tanna Tablets should be given to a pregnant woman only if clearly needed.

Nursing mothers: R-Tanna Tablets should not be administered to a nursing woman.

Adverse Reactions

To report SUSPECTED ADVERSE REACTIONS, contact Meda Pharmaceuticals Inc. at 1-800-526-3840 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.


Adverse effects associated with R-Tanna Tablets at recommended doses have been minimal. The most common have been drowsiness, sedation, dryness of mucous membranes, and gastrointestinal effects. Serious side effects with oral antihistamines or sympathomimetics have been rare.

Overdosage

Signs and symptoms: May vary from CNS depression to stimulation (restlessness to convulsions). Antihistamine overdosage in young children may lead to convulsions and death. Atropine-like signs and symptoms may be prominent.

Treatment: Induce vomiting if it has not occurred spontaneously. Precautions must be taken against aspiration especially in infants, children and comatose patients. If gastric lavage is indicated, isotonic or half-isotonic saline solution is preferred. Stimulants should not be used. If hypotension is a problem, vasopressor agents may be considered.

Dosage and Administration

Administer the recommended dose every 12 hours.

R-Tanna Tablets: Adults -- 1 or 2 tablets.

How Supplied

R-Tanna Tablets (phenylephrine tannate 25 mg, chlorpheniramine tannate 9 mg): buff-colored, capsule-shaped, and imprinted "PRASCO 534" on one side and bisected on the other side. The tablets are available in bottles of 100 (NDC 66993-534-02).


Storage: Store at controlled room temperature 20°-25°C (68°-77°F). Protect from moisture.

Dispense in a tight container.
To report SUSPECTED ADVERSE REACTIONS, contact Meda Pharmaceuticals Inc. at 1-800-526-3840 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

U.S. Patent 6,037,358

Produced under license from

JFC Technologies

Bound Brook, NJ, U.S.A.

U.S. Patents 5,599,846; 5,663,415


Mfd. For: Prasco Laboratories

             Mason, OH 45040 USA

Mfd. By: Meda Pharmaceuticals Inc.

             Somerset, New Jersey 08873-4120


Rev. 05/10

Package Label - Principal Display Panel - 100 Tablet Bottle, R-Tanna Tablets

R-TANNA  phenylephrine tannate and chlorpheniramine tannate  tablet

Product Information Product Type HUMAN PRESCRIPTION DRUG NDC Product Code (Source) 66993-534 Route of Administration ORAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength PHENYLEPHRINE TANNATE (PHENYLEPHRINE) PHENYLEPHRINE TANNATE 25 mg CHLORPHENIRAMINE TANNATE (CHLORPHENIRAMINE) CHLORPHENIRAMINE TANNATE 9 mg

Inactive Ingredients Ingredient Name Strength STARCH, CORN   DIBASIC CALCIUM PHOSPHATE DIHYDRATE   MAGNESIUM STEARATE   METHYLCELLULOSE (1500 CPS)   POVIDONE   TALC

Product Characteristics Color brown (buff) Score 2 pieces Shape CAPSULE Size 15mm Flavor Imprint Code PRASCO534 Contains

Packaging # NDC Package Description Multilevel Packaging 1 66993-534-02 100 TABLET In 1 BOTTLE None

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
unapproved drug other		10/19/2005

Labeler - Prasco Laboratories (065969375)

Establishment
Name	Address	ID/FEI	Operations
Meda Pharmaceuticals, Inc.		005119771	manufacture

Revised: 08/2010Prasco Laboratories

More R-Tanna Tablets resources

• R-Tanna Tablets Side Effects (in more detail)
• R-Tanna Tablets Dosage
• R-Tanna Tablets Use in Pregnancy & Breastfeeding
• Drug Images
• R-Tanna Tablets Drug Interactions
• R-Tanna Tablets Support Group
• 2 Reviews for R-Tannas - Add your own review/rating

Compare R-Tanna Tablets with other medications

• Cold Symptoms
• Hay Fever

Episenta

Episenta may be available in the countries listed below.

UK matches:

• Episenta 150mg and 300mg Prolonged Release Capsules (SPC)
• Episenta 500mg and 1000mg Prolonged Release Granules (SPC)
• Episenta solution for injection (sodium valproate) (SPC)

Ingredient matches for Episenta

Valproic Acid

Valproic Acid sodium (a derivative of Valproic Acid) is reported as an ingredient of Episenta in the following countries:

• United Kingdom

International Drug Name Search

Glossary

SPC	Summary of Product Characteristics (UK)

Click for further information on drug naming conventions and International Nonproprietary Names.

Soval

Soval may be available in the countries listed below.

Ingredient matches for Soval

Valproic Acid

Valproic Acid sodium (a derivative of Valproic Acid) is reported as an ingredient of Soval in the following countries:

• Bangladesh

International Drug Name Search

Sedacoron

Sedacoron may be available in the countries listed below.

Ingredient matches for Sedacoron

Amiodarone

Amiodarone is reported as an ingredient of Sedacoron in the following countries:

• Tunisia

Amiodarone hydrochloride (a derivative of Amiodarone) is reported as an ingredient of Sedacoron in the following countries:

• Austria


• Czech Republic


• Germany


• Hungary


• Lithuania


• Myanmar


• Oman


• Romania


• Russian Federation


• Serbia


• Vietnam

International Drug Name Search

Ipradol

Ipradol may be available in the countries listed below.

Ingredient matches for Ipradol

Hexoprenaline

Hexoprenaline sulfate (a derivative of Hexoprenaline) is reported as an ingredient of Ipradol in the following countries:

• Hong Kong

International Drug Name Search

Trigynovin

Trigynovin may be available in the countries listed below.

Ingredient matches for Trigynovin

Ethinylestradiol

Ethinylestradiol is reported as an ingredient of Trigynovin in the following countries:

• Spain

Gestodene

Gestodene is reported as an ingredient of Trigynovin in the following countries:

• Spain

International Drug Name Search

Osetron

Osetron may be available in the countries listed below.

Ingredient matches for Osetron

Ondansetron

Ondansetron hydrochloride (a derivative of Ondansetron) is reported as an ingredient of Osetron in the following countries:

• Bangladesh


• Myanmar


• Romania


• Sri Lanka

International Drug Name Search

Ektoban

Ektoban may be available in the countries listed below.

In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Ektoban

Cymiazol

Cymiazol is reported as an ingredient of Ektoban in the following countries:

• South Africa

Cypermethrin

Cypermethrin is reported as an ingredient of Ektoban in the following countries:

• South Africa

International Drug Name Search

oxaprozin

ox-a-PROE-zin

Oral route(Tablet)

NSAIDs may cause an increased risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. This risk may be increased in patients with cardiovascular disease or risk factors for cardiovascular disease. Oxaprozin is contraindicated for the treatment of perioperative pain in the setting of CABG surgery. NSAIDs can also cause an increased risk of serious gastrointestinal adverse events especially in the elderly, including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal .

Commonly used brand name(s)

In the U.S.

• Daypro

Available Dosage Forms:

• Tablet

Therapeutic Class: Analgesic

Pharmacologic Class: NSAID

Chemical Class: Propionic Acid (class)

Uses For oxaprozin

Oxaprozin is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain and help relieve symptoms of arthritis (osteoarthritis and rheumatoid arthritis), such as inflammation, swelling, stiffness, and joint pain. oxaprozin does not cure arthritis and will help you only as long as you continue to take it .

oxaprozin is available only with your doctor's prescription .

Before Using oxaprozin

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For oxaprozin, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to oxaprozin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatrics-specific problems that would limit the usefulness of oxaprozin in children 6 to 16 years of age. Safety and efficacy have not been established in children below 6 years of age .

Geriatric

Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of oxaprozin in the elderly. However, elderly patients may be more sensitive to the effects of oxaprozin than younger adults, and are more likely to have age-related kidney problems, which may require adjustment of dosage in patients receiving oxaprozin .

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking oxaprozin, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using oxaprozin with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Ketorolac


• Pentoxifylline

Using oxaprozin with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Abciximab


• Ardeparin


• Argatroban


• Beta Glucan


• Bivalirudin


• Certoparin


• Cilostazol


• Citalopram


• Clopidogrel


• Clovoxamine


• Dabigatran Etexilate


• Dalteparin


• Danaparoid


• Desirudin


• Dipyridamole


• Enoxaparin


• Escitalopram


• Femoxetine


• Flesinoxan


• Fluoxetine


• Fluvoxamine


• Fondaparinux


• Ginkgo


• Heparin


• Lepirudin


• Methotrexate


• Nadroparin


• Nefazodone


• Parnaparin


• Paroxetine


• Pemetrexed


• Protein C


• Reviparin


• Rivaroxaban


• Sertraline


• Sibutramine


• Tacrolimus


• Ticlopidine


• Tinzaparin


• Tirofiban


• Vilazodone


• Zimeldine

Using oxaprozin with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acebutolol


• Acetohexamide


• Alacepril


• Alprenolol


• Amiloride


• Arotinolol


• Atenolol


• Azilsartan Medoxomil


• Azosemide


• Befunolol


• Bemetizide


• Benazepril


• Bendroflumethiazide


• Benzthiazide


• Betaxolol


• Bevantolol


• Bisoprolol


• Bopindolol


• Bucindolol


• Bumetanide


• Bupranolol


• Buthiazide


• Candesartan Cilexetil


• Canrenoate


• Captopril


• Carteolol


• Carvedilol


• Celiprolol


• Chlorothiazide


• Chlorpropamide


• Chlorthalidone


• Cilazapril


• Clopamide


• Cyclopenthiazide


• Cyclosporine


• Delapril


• Desvenlafaxine


• Dilevalol


• Duloxetine


• Enalaprilat


• Enalapril Maleate


• Eprosartan


• Esmolol


• Ethacrynic Acid


• Fosinopril


• Furosemide


• Gliclazide


• Glimepiride


• Glipizide


• Gliquidone


• Glyburide


• Hydrochlorothiazide


• Hydroflumethiazide


• Imidapril


• Indapamide


• Irbesartan


• Labetalol


• Landiolol


• Levobetaxolol


• Levobunolol


• Lisinopril


• Losartan


• Mepindolol


• Methyclothiazide


• Metipranolol


• Metolazone


• Metoprolol


• Milnacipran


• Moexipril


• Nadolol


• Nebivolol


• Nipradilol


• Olmesartan Medoxomil


• Oxprenolol


• Penbutolol


• Pentopril


• Perindopril


• Pindolol


• Piretanide


• Polythiazide


• Propranolol


• Quinapril


• Ramipril


• Sotalol


• Spirapril


• Spironolactone


• Talinolol


• Tasosartan


• Telmisartan


• Temocapril


• Tertatolol


• Timolol


• Tolazamide


• Tolbutamide


• Torsemide


• Trandolapril


• Triamterene


• Trichlormethiazide


• Valsartan


• Venlafaxine


• Xipamide


• Zofenopril

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of oxaprozin. Make sure you tell your doctor if you have any other medical problems, especially:

• Anemia or


• Asthma or


• Bleeding problems or


• Blood clots or


• Edema (fluid retention or body swelling) or


• Heart attack, history of or


• Heart disease (e.g., congestive heart failure) or


• High blood pressure or


• Kidney disease or


• Liver disease (e.g., hepatitis) or


• Stomach or intestinal ulcers or bleeding or


• Stroke, history of—Use with caution. oxaprozin may make these conditions worse .

• Aspirin sensitivity, history of—oxaprozin should NOT be used in patients with this condition .

• Dehydration—Should be treated first before starting treatment with oxaprozin .

• Heart surgery (e.g., coronary artery bypass graft [CABG] surgery)—oxaprozin should NOT be used to relieve pain right before or after the surgery .

Proper Use of oxaprozin

For safe and effective use of oxaprozin, do not take more of it, do not take it more often, and do not take it for a longer time than ordered by your doctor. Taking too much of oxaprozin may increase the chance of unwanted effects, especially in elderly patients .

When used for severe or continuing arthritis, oxaprozin must be taken regularly as ordered by your doctor in order for it to help you. oxaprozin usually begins to work within one week, but in severe cases up to two weeks or even longer may pass before you begin to feel better. Also, several weeks may pass before you feel the full effects of oxaprozin.

Dosing

The dose of oxaprozin will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of oxaprozin. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (tablets):
  
  • For osteoarthritis and rheumatoid arthritis:
    
    • Adults—1200 milligrams (mg) (two 600-mg tablets) once a day.
    
    
    • Children 6 to 16 years of age—Dose is based on body weight and must be determined by your doctor.
    
    
    • Children below 6 years of age—Use and dose must be determined by your doctor .
    
    
  
  

Missed Dose

If you miss a dose of oxaprozin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using oxaprozin

It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. Blood and urine tests may be needed to check for unwanted effects .

oxaprozin may raise your risk of having a heart attack or stroke. This is more likely in people who already have heart disease. People who use oxaprozin for a long time might also have a higher risk .

oxaprozin may cause bleeding in your stomach or intestines. These problems can happen without warning signs. This is more likely if you have had a stomach ulcer in the past, if you smoke or drink alcohol regularly, if you are over 60 years old, if you are in poor health, or if you are using certain other medicines (a steroid or a blood thinner) .

Serious skin reactions can occur during treatment with oxaprozin. Check with your doctor right away if you have any of the following symptoms while taking oxaprozin: blistering, peeling, loosening of skin, chills, cough, diarrhea, fever, itching, joint or muscle pain, red skin lesions, sore throat, sores, ulcers, white spots in mouth or on lips, or unusual tiredness or weakness .

Possible warning signs of some serious side effects that can occur during treatment with oxaprozin may include swelling of the face, fingers, feet, and/or lower legs; severe stomach pain, black, tarry stools, and/or vomiting of blood or material that looks like coffee grounds; unusual weight gain; yellow skin or eyes; decreased urination; unusual bleeding or bruising; and/or skin rash. Also, signs of serious heart problems could occur such as chest pain, tightness in chest, fast or irregular heartbeat, unusual flushing or warmth of skin, weakness, or slurring of speech. Stop taking oxaprozin and check with your doctor immediately if you notice any of these warning signs .

oxaprozin may also cause a serious type of allergic reaction called anaphylaxis. Although this is rare, it may occur more often in patients who are allergic to aspirin or to any of the nonsteroidal anti-inflammatory drugs. Anaphylaxis requires immediate medical attention. The most serious signs of this reaction are very fast or irregular breathing, gasping for breath, wheezing, or fainting. Other signs may include changes in color of the skin of the face; very fast but irregular heartbeat or pulse; hive-like swellings on the skin; and puffiness or swellings of the eyelids or around the eyes. If these effects occur, get emergency help at once .

Using oxaprozin while you are pregnant can harm your unborn baby. If you think you have become pregnant while using the medicine, tell your doctor right away .

oxaprozin may make your skin more sensitive to sunlight. Use a sunscreen when you are outdoors. Avoid sunlamps and tanning beds .

Before having any kind of surgery or medical tests, tell your doctor that you are taking oxaprozin. It may be necessary for you to stop treatment for a while, or to change to a different nonsteroidal anti-inflammatory drug before your procedure .

oxaprozin Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Skin rash

Less common

• Bloating


• bloody or black, tarry stools


• burning upper abdominal pain


• burning while urinating


• cloudy urine


• constipation


• decrease in urine output or decrease in urine-concentrating ability


• diarrhea


• difficult or painful urination


• frequent urination


• headache


• heartburn


• indigestion


• itching skin


• loss of appetite


• nausea or vomiting


• pale skin


• severe abdominal pain, cramping, or burning


• severe and continuing nausea


• swelling


• troubled breathing with exertion


• unusual bleeding or bruising


• unusual tiredness or weakness


• vomiting of blood or material that looks like coffee grounds


• weight loss

Rare

• Agitation


• bleeding gums


• blistering, peeling, loosening of skin


• blurred vision


• body aches or pain


• burning feeling in chest or stomach


• changes in blood pressure


• chest pain


• clay-colored stools


• coma


• confusion


• cough or hoarseness


• cracks in the skin


• dark urine


• depression


• difficult or labored breathing


• difficulty swallowing


• dilated neck veins


• dizziness


• ear congestion


• extreme fatigue


• fainting


• feeling of discomfort


• fever or chills


• fluid-filled skin blisters


• high fever


• hives or welts


• hostility


• increased sensitivity of skin to sunlight


• increased thirst


• increased volume of pale, dilute urine


• inflammation of joints


• irregular, fast or slow, or shallow breathing


• irritability


• joint or muscle pain


• large, flat, blue or purplish patches in the skin


• large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs


• lethargy


• light-colored stools


• lightheadedness


• loss of heat from the body


• loss of voice


• lower back or side pain


• muscle aches


• muscle twitching


• nasal congestion


• nervousness


• noisy breathing


• pain or burning in throat


• pain or tenderness around eyes and cheekbones


• pale or blue lips, fingernails, or skin


• pinpoint red or purple spots on skin


• pounding in the ears


• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue


• rapid weight gain


• red skin lesions, often with a purple center


• red, irritated eyes


• redness or other discoloration of skin


• redness, swelling, or soreness of tongue


• scaly skin


• seizures


• severe sunburn


• shortness of breath


• skin thinness


• slow, fast, irregular, pounding, or racing heartbeat or pulse


• sneezing


• sore throat


• sores, ulcers, or white spots on lips or tongue or inside the mouth


• stomach upset


• stuffy or runny nose


• stupor


• swelling of face, fingers, feet, or lower legs


• swelling or inflammation of the mouth


• swollen lymph glands


• tenderness in stomach area


• tightness in chest


• unpleasant breath odor


• upper right abdominal pain


• wheezing


• yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Acid or sour stomach


• belching


• stomach discomfort

Less common

• Continuing ringing or buzzing or other unexplained noise in ears


• excess air or gas in stomach or intestines


• hearing loss


• passing gas


• relaxed and calm


• sleepiness or unusual drowsiness


• trouble sleeping

Rare

• Anxiety


• burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings


• burning, dry, or itching eyes


• change in taste


• decreased hearing


• discharge, excessive tearing


• dry mouth


• feeling of constant movement of self or surroundings


• general feeling of discomfort or illness


• lack or loss of strength


• redness, pain, swelling of eye, eyelid, or inner lining of eyelid


• sensation of spinning


• shakiness in legs, arms, hands, feet


• sleeplessness


• trembling or shaking of hands or feet


• unable to sleep

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: oxaprozin side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More oxaprozin resources

• Oxaprozin Side Effects (in more detail)
• Oxaprozin Dosage
• Oxaprozin Use in Pregnancy & Breastfeeding
• Drug Images
• Oxaprozin Drug Interactions
• Oxaprozin Support Group
• 5 Reviews for Oxaprozin - Add your own review/rating

• oxaprozin Concise Consumer Information (Cerner Multum)


• Oxaprozin Prescribing Information (FDA)


• Oxaprozin Monograph (AHFS DI)


• Oxaprozin Professional Patient Advice (Wolters Kluwer)


• Oxaprozin MedFacts Consumer Leaflet (Wolters Kluwer)


• Daypro Prescribing Information (FDA)

Compare oxaprozin with other medications

• Juvenile Rheumatoid Arthritis
• Osteoarthritis
• Rheumatoid Arthritis