Deconamine

Pronunciation: klor-fen-IHR-ah-meen/sue-do-eh-FED-rin
Generic Name: Chlorpheniramine/Pseudoephedrine
Brand Name: Examples include Deconamine and Sudafed Plus

Deconamine is used for:

Relieving symptoms of sinus congestion, sinus pressure, runny nose, and sneezing due to colds, upper respiratory infections, and allergies. It may also used to treat other conditions as determined by your doctor.

Deconamine is an antihistamine and decongestant combination. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing. The decongestant promotes sinus and nasal drainage, relieving congestion and pressure.

Do NOT use Deconamine if:

• you are allergic to any ingredient in Deconamine


• you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems


• you take sodium oxybate (GHB) or if you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Deconamine:

Some medical conditions may interact with Deconamine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a fast, slow, or irregular heartbeat


• if you have a history of asthma, lung problems (eg, emphysema), adrenal gland problems (eg, adrenal gland tumor), heart problems, high blood pressure, diabetes, heart blood vessel problems, stroke, glaucoma, a blockage of your stomach or intestines, ulcers, a blockage of your bladder, trouble urinating, an enlarged prostate, seizures, or an overactive thyroid

Some MEDICINES MAY INTERACT with Deconamine. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin,MAOIs (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Deconamine's side effects


• Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased


• Bromocriptine or hydantoins (eg, phenytoin) because the risk of their side effects may be increased by Deconamine


• Guanethidine, guanadrel, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Deconamine

This may not be a complete list of all interactions that may occur. Ask your health care provider if Deconamine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Deconamine:

Use Deconamine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Deconamine by mouth with or without food.


• If you miss a dose of Deconamine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Deconamine.

Important safety information:

• Deconamine may cause dizziness, drowsiness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Deconamine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Do not take diet or appetite control medicines while you are taking Deconamine without checking with you doctor.


• Deconamine has pseudoephedrine and chlorpheniramine in it. Before you start any new medicine, check the label to see if it has pseudoephedrine or chlorpheniramine in it too. If it does or if you are not sure, check with your doctor or pharmacist.


• Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.


• If your symptoms do not get better within 5 to 7 days or if they get worse, check with your doctor.


• Deconamine may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Deconamine. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.


• Deconamine may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Deconamine for a few days before the tests.


• Tell your doctor or dentist that you take Deconamine before you receive any medical or dental care, emergency care, or surgery.


• Use Deconamine with caution in the ELDERLY; they may be more sensitive to its effects.


• Caution is advised when using Deconamine in CHILDREN; they may be more sensitive to its effects.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Deconamine while you are pregnant. It is not known if Deconamine is found in breast milk. Do not breast-feed while taking Deconamine.

Possible side effects of Deconamine:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; trouble sleeping; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Deconamine side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; severe dizziness, lightheadedness, or headache; severe drowsiness; seizures; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Deconamine:

Store Deconamine at room temperature, between 59 and 86 degrees F (15 and 30 degrees C) away from heat, moisture, and light. Do not store in the bathroom. Keep Deconamine out of the reach of children and away from pets.

General information:

• If you have any questions about Deconamine, please talk with your doctor, pharmacist, or other health care provider.


• Deconamine is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Deconamine. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Deconamine resources

• Deconamine Side Effects (in more detail)
• Deconamine Use in Pregnancy & Breastfeeding
• Deconamine Drug Interactions
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Dyrenium

Pronunciation: trye-AM-ter-een
Generic Name: Triamterene
Brand Name: Dyrenium

Dyrenium may cause high blood potassium levels that can be fatal if not corrected. High blood potassium levels occur more commonly in patients with kidney problems, diabetes, elderly patients, those who are severely ill, or patients who are not taking an agent used to increase excretion of potassium. If you develop muscle weakness or irregular heartbeat, notify your doctor immediately.

Dyrenium is used for:

Treating swelling (edema) associated with conditions such as congestive heart failure, cirrhosis of the liver, and certain severe kidney problems (eg, nephrosis). It may be used alone or with other medicines. It may also be used for other conditions as determined by your doctor.

Dyrenium is a potassium-sparing diuretic. It works by making the kidneys eliminate sodium (salt) and water from the body while retaining potassium.

Do NOT use Dyrenium if:

• you are allergic to any ingredient in Dyrenium


• you are taking potassium supplements, another potassium-sparing diuretic (eg, amiloride), or an aldosterone blocker (eg, eplerenone)


• you are unable to urinate or have high blood potassium levels or severely decreased liver or kidney function

Contact your doctor or health care provider right away if any of these apply to you.

Before using Dyrenium:

Some medical conditions may interact with Dyrenium. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have heart problems, diabetes, kidney damage caused by diabetes, liver or kidney problems, low blood sodium levels, a high acidity of body fluids, dehydration, or a history of kidney stones

Some MEDICINES MAY INTERACT with Dyrenium. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Aldosterone blockers (eg, eplerenone), angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), angiotensin II receptor antagonists (eg, valsartan), cyclosporine, penicillin G potassium, otherpotassium-sparing diuretics (eg, amiloride), or potassium supplements because high blood potassium levels may occur and cause listlessness, confusion, abnormal skin sensations of the arms and legs, heaviness of the limbs, slow or irregular heartbeat, or stopping of the heart


• Insulin and oral hypoglycemics (eg, chlorpropamide) because the risk of side effects, such as severe low blood sodium and changes in blood sugar, may be increased


• Lithium because risk of side effects and toxicity may be increased by Dyrenium


• Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, indomethacin) because the effectiveness of Dyrenium may be decreased and the risk of kidney problems and high blood potassium levels may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Dyrenium may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Dyrenium:

Use Dyrenium as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Dyrenium by mouth with or without food.


• Dyrenium may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm.


• If you miss a dose of Dyrenium, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Dyrenium.

Important safety information:

• Dyrenium may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Dyrenium with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Check with your doctor before you use a salt substitute or a product that has potassium in it.


• Tell your doctor or dentist that you take Dyrenium before you receive any medical or dental care, emergency care, or surgery.


• LAB TESTS, including blood electrolytes, blood cell counts, kidney and liver function tests, blood uric acid levels, and blood pressure, may be performed while you use Dyrenium. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Use Dyrenium with caution in the ELDERLY; they may be more sensitive to its effects.


• Dyrenium should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: It is not known if Dyrenium can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Dyrenium while you are pregnant. It is not known if Dyrenium is found in breast milk. Do not breast-feed while taking Dyrenium.

Possible side effects of Dyrenium:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; headache; loss of appetite; nausea; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); dry mouth; excessive thirst; slow or irregular heart rate; unusual muscle weakness; unusual tiredness; vomiting; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Dyrenium side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include lightheadedness; nausea; vomiting; weakness.

Proper storage of Dyrenium:

Store Dyrenium at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Dyrenium out of the reach of children and away from pets.

General information:

• If you have any questions about Dyrenium, please talk with your doctor, pharmacist, or other health care provider.


• Dyrenium is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Dyrenium. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

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• Dyrenium Side Effects (in more detail)
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